WebApr 11, 2024 · This study revealed the key mechanism of NK cells dysfunction and immune evasion from the perspective of membrane topology, providing a new strategy for NK cell-based tumor immunotherapy. Reference: Zheng X, Hou Z, Qian Y, et al. Tumors evade immune cytotoxicity by altering the surface topology of NK cells. Nat Immunol. WebJun 30, 2014 · Abstract. Natural killer (NK) cells are normal white blood cells capable of killing malignant cells without prior sensitization. Allogeneic NK cell infusions are attractive for cancer therapy because of non–cross-resistant mechanisms of action and minimal overlapping toxicities with standard cancer treatments. Although NK therapy is promising, …
Human natural killer cells - American Society of Hematology
WebApr 12, 2024 · Natural killer cells: Warriors against malaria. Malaria remains a public health threat. Recently in Science Translational Medicine, Ty et al. and Odera et al. independently … WebB cells, cells of the innate immune response, including natural killer (NK) cells, do not express RAG proteins and are therefore incapa-ble of rearrangement of variable-(diversity)-joining gene segments. ... late and expanded to include protective antiviral immunity12,13,27. However, many questions remain unanswered. Arguably, identifica- how to search for similar websites
Natural killer cells: Warriors against malaria: Cell Host
WebApr 12, 2024 · Natural killer (NK) cells play key roles in eliminating pathogen-infected cells. Verbena officinalis (V. officinalis) has been used as a medical plant in traditional and modern medicine for its anti-tumor and anti-inflammatory activities, but its effects on immune responses remain largely elusive. This study aimed to investigate the potential of … WebNatural killer (NK) cells selectively lyse cells without requiring prior activation. NK cells belong to a family of innate lymphoid cells (ILCs), which are critical for immune … WebNov 26, 2004 · Natural killer (NK) cells are lymphocytes of the innate immune system that are involved in early defenses against both allogeneic (nonself) cells and autologous cells undergoing various forms of stress, such as infection with viruses, bacteria, or parasites or malignant transformation. how to search for someone